Interleukin-18 and Macrophage Migration Inhibitory Factor Are Associated With Increased Carotid Intima–Media Thickening

Increased circulating macrophage migration inhibitory factor levels are associated with coronary artery disease

BACKGROUND To evaluate the macrophage migration inhibitory factor and E-selectin levels in patients with acute coronary syndrome. MATERIALS/METHODS We examined the plasma migration inhibitory factor and E-selectin levels in 87 patients who presented with chest pain at our hospital. The patients were classified into two groups according to their cardiac status. Sixty-five patients had acute my...

Macrophage Migration Inhibitory Factor

Correlation between urine macrophage migration inhibitory factor (MIF)/creatinine ratio and time after kidney transplantation

 Abstract  Background: Despite the long-standing association of macrophage migration inhibitory  factor (MIF) with delayed-type hypersensitivity response, the potential role  of MIF in chronic allograft nephropathy is unknown. The association between upregulation of MIF expression, macrophage and T cell infiltration and the severity of  chronic allograft nephropathy suggests that MIF may be an ...

Migration inhibitory factor and macrophage bactericidal function.

A homogeneous population of immunologically active lymphocytes was obtained from peritoneal exudates of guinea pigs with delayed hypersensitivity to bovine gamma globulin (BGG). The lymphocytes were cultured with and without BGG for 24 hr, and cell-free supernatant fluids were then assayed simultaneously for their ability to influence two in vitro parameters of macrophage function: migration fr...

Glucocorticoid Suppression of Macrophage Migration Inhibitory Factor

The ability of hydrocortisone to modify antigen-mediated inhibition of macrophage migration, an in vitro correlate of cellular immunity in the guinea pig, was investigated. Only the glucocorticoids, hydrocortisone and dexamethasone, significantly blocked migration inhibitory factor (MIF) activity in pharmacologic concentrations. Hydrocortisone had no effect on antigen "processing" by macrophage...